In our laboratory, we have used HR-CGH as a screening method for cryptic chromosomal imbalances for several years. In an initial study, we found a cryptic chromosomal imbalance in 5 out of 50 patients ...

In this study we addressed the question whether MDS with normal karyotype in chromosome banding analysis harbor cytogenetically cryptic gains or losses detectable by array CGH. A total of 520 patients ...

为探究儿童急性淋巴细胞白血病（ALL）的发病机制，研究人员对 67 例马来西亚正常核型的儿童 ALL 患者开展基于阵列比较基因组杂交（array-CGH）研究。结果发现了致病性拷贝数变异（CNVs）和意义不明变异（VUS），这有助于白血病分类和个性化治疗123。 儿童急性 ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

We previously reported that mice chronically irradiated with low-dose-rate γ rays had significantly shorter mean life spans than nonirradiated controls. This life shortening appeared to be due ...

SANTA CLARA, Calif.--(BUSINESS WIRE)--Agilent Technologies Inc. (NYSE:A) today announced that scientists using the company’s comparative genomic hybridization (CGH) technology have shown that cancer ...

infoQuant Ltd brings microarray technology closer to clinical use with its latest release of copy number analysis and interpretation software "oneClickCGH" and "CGH Fusion" for microarray-based ...

In addition to the surprising revelation that our chromosomes harbor fewer genes than originally predicted, the Human Genome Project also unveiled that all individuals share approximately 99.9% of ...

Predictors of survival in advanced renal cell carcinoma (RCC): Long-term results from Southwest Oncology Group trial S8949 No significant financial relationships to disclose. This is an ASCO Meeting ...

Subgroup analysis of a randomized, phase III study of the effect of denosumab in women with nonmetastatic breast cancer receiving aromatase inhibitor (AI) therapy No significant financial ...