It is now commonly accepted that solid primary cancers, including urothelial tumours and cancer of the colon, breast, and lung, arise due to a multistep process involving the accumulation of genetic ...

PCR primers were designed in an average distance of 0.7 kb upstream and downstream of each predicted junction and amplifications were performed using standard protocols of Promega Master Mix (Promega ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

We previously reported that mice chronically irradiated with low-dose-rate γ rays had significantly shorter mean life spans than nonirradiated controls. This life shortening appeared to be due ...

In addition to the surprising revelation that our chromosomes harbor fewer genes than originally predicted, the Human Genome Project also unveiled that all individuals share approximately 99.9% of ...

Recent advances in gene analysis technology have been remarkable, and many technologies that can be easily introduced in each in-house laboratory have been developed. Especially a comprehensive gene ...

Intermittent high-dose intravenous interferon alpha 2b (IFNa2b) for adjuvant treatment of stage III malignant melanoma: An interim analysis of a randomized phase III study (NCT00226408) ...