We are living in an era where biology has become synonymous with big data due to the ever-increasing amount of data being generated by technologies such as next-generation sequencing. Bioinformatics ...

We resent it when preliminary or ancillary work occupies so much of our attention that our real work, or what we consider to be our real work, recedes. No less a figure than Enrico Fermi, when ...

Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...