To protect themselves against viral infection, bacteria often use CRISPR-Cas systems to identify and destroy an invading virus’s genetic material. But viruses aren’t helpless and can deploy ...

本研究提出了一种基于错配 crRNA 的 CRISPR/Cas12a 检测平台，实现了对 kelch13 基因 Q613、Q613E 和 Q613H ...

Scientists study a molecular machine that moves jumping genes in DNA, paving the way for a new gene editing tool beyond ...

The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems A team of researchers led by Feng Zhang at the Broad ...

Professor of Biomedical Engineering, Head of Biomedical Engineering Programme, Director of CUHKSZ-Boyalife Joint Laboratory of Regenerative Medicine Engineering, Team Leader of Integrated Devices and ...

The lack of efficient delivery methods is a major barrier to clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas)-mediated genome editing in many plant ...

A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies. An international team of ...

A genetic editing system similar to CRISPR-Cas9 has been uncovered for the first time in eukaryotes – the group of organisms that include fungi, plants, and animals. The system, based on a protein ...

The recent publication in Science by Mogila, Tamulaitiene et al. represents a continuation of the successful scientific research conducted by Gintautas Tamulaitis' group. In this study, the Vilnius ...

Employing a metagenomic search, we identified a family of miniature CRISPR-Cas type V-L systems capable of RNA-guided dsDNA target cleavage without a tracrRNA. A bacterial depletion screen revealed ...

Another potentially game-changing discovery has come out of the lab of Feng Zhang, PhD. This time, they uncovered the first programmable RNA-guided system in eukaryotes. Just a few months ago, the ...