Colorectal cancer (CRC) can be characterized as sporadic, familial, or hereditary. The American Cancer Society expects ~142,000 new cases of CRC in 2013. It is estimated that 20–30% of all CRCs are ...

Cancer is a disease of the genome resulting from a combination of genetic modifications, or mutations. We inherit from our parents strong or weak predispositions to developing certain kinds of cancer; ...

An estimated 10% of breast and ovarian cancers result from hereditary causes. Current testing guidelines for germ line susceptibility genes in patients with breast carcinoma were developed to identify ...