Although high-density SNP-typing arrays allow determination of CNAs at a resolution of <100 kbp, it is not a simple task to link such data to changes in the number of the corresponding genes. The ...

Defining regions of genomic imbalance can identify genes involved in tumour development. Conventional cytogenetics has identified several nonrandom copy number alterations (CNA) in uveal melanomas ...

JA Rosenfeld is an employee of Signature Genomic Laboratories, a subsidiary of PerkinElmer, Inc. The authors have no other relevant affiliations or financial involvement with any organization or ...