Without altering the genetic code in the DNA, epigenetic modifications can change how genes are expressed, affecting an organism's health and development. The once radical idea that such changes in ...

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

The biomedical literature provides many examples when medical conditions that were classically viewed as a paradigm for genetic inheritance appear to be shaped by additional factors, which cannot be ...

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens. Scientists at the German Cancer Research Center (Deutsches ...

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...

Researchers have discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development. This finding ...

A study by researchers at UC Santa Cruz has demonstrated how a common type of epigenetic modification can be transmitted via sperm not only from parents to offspring, but to the next generation ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...