Nonspecific histone deacetylase (HDAC) inhibition has been shown to facilitate the extinction of drug-seeking behavior in a manner resistant to reinstatement. A key open question is which specific ...

Drug abstinence is frequently compromised when addicted individuals are re-exposed to environmental stimuli previously associated with drug use. Research with human addicts and in animal models has ...

One of the main influences on our behavior is the consequences of our actions, especially those that come shortly after we perform that action. For example, when a behavior is followed by positive and ...