Computational protein design—the automated search for amino acid sequences with defined three-dimensional structures—opens exciting possibilities for the engineering of biomolecules with desired ...

Metalloproteins account for nearly half of all proteins in nature. Protein metal-binding sites are responsible for catalysing important biological processes, such as photosynthesis, respiration, water ...

It's often been said that form follows function. I prefer to think that function drives form. Unfortunately, just the opposite is true for modern CAD tools -- function is a slave to form (or geometry) ...

A recent Aberdeen Group study showed that best-in-class manufacturers — those that get products to market faster with the lowest change costs — build about half the number of physical prototypes than ...

Members can download this article in PDF format. Intelligent robotic systems are bringing great gains in productivity to the factory floor. However, they also present collision hazards that could ...

What are software test libraries? The key role of diagnostic coverage in characterizing safety-mechanism effectiveness. How to approach target values. The magic behind today’s astonishing automotive ...

For his interiors studio, the designer Alfredo Paredes leases a 2,250-square-foot penthouse loft with an enormous skylight on ...

Do you need a design or functional specification? It depends on who your audience is and where you are in the product development cycle. People often confuse the purpose and role of functional ...

People often confuse the purpose and role of functional specifications and design documents. Design and function should never meet in a document. Design and function must be documented during the ...