One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...

Researchers have identified gene-regulatory variants that might have contributed to Neanderthals’ beefy jaws — offering a window on how the human face developed 1. This ‘non-coding’ sequence controls ...

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...