Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

In a new study, researchers compare the transcriptomic profiles of recently reported human embryo stage 8-cell-like cells with human embryos The onset of embryo-specific gene transcription, also known ...

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Two to three weeks after conception, an embryo faces a critical point in its development. In the stage known as gastrulation, the transformation of embryonic cells into specialized cells begins. This ...

When Berna Sozen, PhD, assistant professor of Developmental Stem Cell Biology at Yale, was in her first weeks of pregnancy, she couldn’t help but wonder about what exactly was going on in the “black ...

It's one of life's most defining moments - that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage ...

Researchers have discovered a potential 'pause button' in the earliest stages of human development. Whether humans can control the timing of their development has long been debated. The new study ...

Researchers have used naïve pluripotent stem cells to create an embryo model that looks and acts like a natural human embryo. They say it’s an ethical way of gaining a better understanding of ...