When designing programs or software for the implementation of Monte Carlo (MC) hypothesis tests, we can save computation time by using sequential stopping boundaries. Such boundaries imply stopping ...

Covariate-adaptive designs are often implemented to balance important covariates in clinical trials. However, the theoretical properties of conventional testing hypotheses are usually unknown under ...

Gating indicators recommended by CDC for phased reopening following COVID-19 shutdowns include “sustained decreases” or a “downward trajectory…over a 14-day period” in public health statistics. These ...