Researchers have identified key factors that promote the reprogramming of human stem cells to the naïve state, which can be used to model the earliest stages of development. This new knowledge will ...

Tsukuba, Japan - Once damaged, the human heart does a poor job of repairing itself, so this is a key priority for treating heart failure. One way of restoring cardiac function is to reprogram ...

Researchers have developed a high-throughput screening system to identify the NSAID diclofenac as a factor responsible for enhancing cardiac reprogramming in postnatal and adult fibroblasts.