Defining regions of genomic imbalance can identify genes involved in tumour development. Conventional cytogenetics has identified several nonrandom copy number alterations (CNA) in uveal melanomas ...

Schizophrenia is a common psychiatric disorder involving approximately 1% of the population worldwide. Family, twin, and adoption studies suggest genetic factors contribute to this illness (Lang et al ...

Agilent Technologies Inc. has announced that scientists using an Agilent custom-designed comparative genomic hybridization (CGH) array have sequenced the entire gene map of a Korean male. An ...

October 19, 2011 (Montreal, Quebec) — Investigators at the University of Pittsburgh have developed a comparative genome hybridization (CGH) microarray that offers significantly superior resolution and ...

Chromosome rearrangements are commonly associated with multiple disease states such as cancer and many developmental syndromes, including Down’s syndrome and autism spectrum disorders. The ...

Due to its higher resolution, oligo array CGH has recently made strong inroads in the cytogenetic lab. It’s not surprising. With an increased sensitivity of more than 1,000-fold, microarrays can ...