本研究针对血吸虫病治疗药物单一、耐药性风险高等问题，系统开展了非寄生虫基因组编码RNA (ngRNA)在日本血吸虫 (S.japonicum)致病性调控中的作用研究。研究人员通过宏转录组学、单细胞RNA测序等技术，首次发现4种ngRNA通过编码RNA依赖性RNA聚合酶 (RdRp)调控血吸虫卵巢发育和产卵过程，并证实靶向rp1 ...

Discover how AI is revolutionizing RNA drug development in a new article published in Engineering. Learn about the potential ...

PHILADELPHIA, PA—Zilebesiran (Alnylam), an investigational therapeutic agent that interferes with messenger RNA to stop the production of angiotensinogen (AGT), lowers systolic blood pressure levels ...

RNA interference – RNAi – functions specifically to silence, or deactivate, genes. Among other applications, it promises to be groundbreaking as a way to treat infections of bees by a commercially ...