Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older. The disease has proven difficult to develop new treatments for, and available ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, No. 16 (Aug. 15, 1986), pp. 5919-5923 (5 pages) Yeast cells contain a protein of molecular size 70 kDa that ...

Jerold Chun, MD, PhD, is a professor in the Center for Neurologic Diseases at Sanford Burnham Prebys and the senior and corresponding author of the manuscript. Alzheimer’s disease is the most common ...

Bodnar, AG, Ouellette, M, Frolkis, M, Holt, SE, Chiu, CP, Morin, GB, Harley, CB, Shay, JW, Lichtsteiner, S & Wright, WE (1998). Extension of life-span by introduction ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--ROME Therapeutics, a biotechnology company harnessing the repeatome for drug development, today announced new preclinical data demonstrating the ability of ...

Prime editing uses CRISPR-guided reverse transcription to enable the programmable introduction of any desired base substitution or small insertion or deletion. One challenge for using prime editing ...

Crossbow Therapeutics Inc. has provided details on the preclinical characterization for the telomerase reverse transcriptase (TERT)-targeting T-cell engager CBX-663.