'Inheritance through homology' is the most common and generally more accessible approach to function prediction, but orthology should be established where possible to improve confidence in predictions ...

Plasma triglyceride levels are heritable and are correlated with the risk of coronary heart disease. Sequencing of the protein-coding regions of the human genome (the exome) has the potential to ...

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

Gain-of-function research (GOFR) refers to the serial passaging of microorganisms to increase their transmissibility, virulence, immunogenicity, and host tropism by applying selective pressure to a ...

The work has helped in the development of mRNA coronavirus vaccines and the first approved covid drug. In May, the longtime coronavirus researcher Ralph Baric found himself at the center of the ...

Have you ever found yourself endlessly dragging that little Excel fill handle, trying to populate rows or columns with numbers, dates, or formulas? It’s tedious, time-consuming, and let’s be ...

If you usually work with non-trivial C sources, you may have wondered which execution path (that is, which sequence of function calls) brought you to a certain point in your program. Also, it would be ...