T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

"T cells' capability to fully prevent acute viral infections opens new avenues for vaccine development." ScienceDaily. www.sciencedaily.com / releases / 2025 / 01 / 250110121913.htm (accessed December ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

Flagship Pioneering, a scientific innovation engine for transformative platforms and products, today announced a research program under its strategic collaboration with Pfizer whereby Flagship-founded ...

Researchers at the Johns Hopkins Kimmel Cancer Center’s Ludwig Center developed a new treatment that selectively targets ...

At the recent American Society of Hematology annual meeting, researchers presented preclinical data examining how ...

As the CSO for genomic medicine at Cytiva, I have numerous interactions with our customers, and I attend many scientific and industry events. It’s great to be able to get first-hand exposure to what ...

Neoantigens are unique markers that distinguish only cancer cells. By adding B cell reactivity, cancer vaccines can move ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...