Enhancers are genetic elements that have major roles in determining cell type-specific gene expression patterns and responses to internal and external signals. Mammalian genomes contain millions of ...

A new study suggests that one of the most common diabetes treatments may speed type 2 diabetes progression by causing insulin-producing cells to lose their functional identity. Sulphonylureas have bee ...

Type 1 diabetes is caused by insulin deficiency resulting from immune-mediated destruction of pancreatic beta cells. Its cause is multifactorial, with complex genetic factors and a strong influence of ...

Teplizumab, a humanized monoclonal antibody to CD3 on T cells, is approved by the Food and Drug Administration to delay the onset of clinical type 1 diabetes (stage 3) in patients 8 years of age or ...

Many medical problems, such as traumatic brain injuries, stroke, dementia, and even cancer, can affect the brain and make it difficult for someone to think or process information. Cognitive ...

Biosafety hawks were initially optimistic that the incoming second Trump administration would at last place binding constraints on so-called "dangerous gain-of-function" research, in which pathogens ...