This is a preview. Log in through your library . Abstract N⁶-methyladenosine (m⁶A) is the most abundant internal messenger RNA (mRNA) modification, contributing to the processing, stability, and ...

RNA—in the form of messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA)—transforms the genome coded by DNA into proteins that form the backbone of all cellular functions. However, ...

Researchers have discovered that a chemical modification to the synthetic messenger RNA used in therapeutics can cause the cell’s machinery to misread its instructions and result in unintended immune ...

N 6-methyladenosine (m 6 A) is the most extensive studied RNA modification across various species, and the important effect of m 6 A modification in immune system has been revealed in distinct ...

Duke researchers published a breakthrough in understanding m6A through the development of a genetically encoded sensor for the most abundant internal mRNA modification. These mRNA modifications are ...

N4-Acetylation of cytidine (ac4C) is an mRNA modification that enhances cellular mRNA stability and translation. Most eukaryotic organisms catalyze ac4C using a homologue of human N-acetyltransferase ...