The planned implementation of Medicaid work requirements provides an opportunity to obtain longitudinal data to guide Medicaid policy, including data on health consequences for people who lose ...

A 30-year-old woman presented with a 10-week history of painful skin nodules and a 6-week history of fevers and night sweats. A physical examination was notable for palpable subcutaneous nodules ...

Tobacco use kills more than 7 million people worldwide each year, including 1.3 million who die from the effects of exposure to secondhand smoke.1 As a major contributor to cancer, cardiovascular ...

Patients benefit from antiplatelet therapy after coronary-artery bypass grafting (CABG) for an acute coronary syndrome.

An appropriate duration of dual antiplatelet therapy after percutaneous coronary intervention for acute myocardial infarction ...

Beta-blockers have been the initial treatment for symptomatic obstructive hypertrophic cardiomyopathy (HCM) despite limited ...

Poorly controlled hypertension is a common problem worldwide, particularly in low-resource settings. We conducted an ...

In this international, randomized trial, we assigned critically ill adults who were undergoing invasive ventilation to receive intravenous pantoprazole (at a dose of 40 mg daily) or matching placebo.

A 61-year-old woman presented to the emergency department with chest pain. ST-segment elevations were revealed on ECG. A coronary angiogram showed normal coronary arteries, but left ventriculography ...

Patients who have taken opioids for years for chronic pain must be treated differently from those who have not because such therapies cause profound physiological and neurologic changes. Reflexive ...

Welcome and thank you for considering the New England Journal of Medicine (NEJM) as a venue for your work. As the oldest continuously-published medical journal, our mission since 1812 has been to ...

Sodium–glucose cotransporter 2 inhibitors reduce the risk of hospitalization for heart failure in patients with heart failure and a reduced ejection fraction, but their effects in patients with heart ...