Heart failure is a pressing worldwide public-health problem with millions of patients having worsening heart failure. Despite all the available therapies, the condition carries a very poor prognosis.

The centrosome is the major microtubule-organizing centre (MTOC) in eukaryotic cells, being comprised of two centrioles surrounded by an electron-dense matrix, the pericentriolar material (PCM). The ...

Coffee contains caffeine and other bioactive compounds, including antioxidants like chlorogenic acids plus cafestol, kahweol, and trigonelline, though amounts vary per cup. Caffeine blocks adenosine, ...