Driving Fatigue Prevention Driver fatigue mimics alcohol impairment and compromises drivers’ alertness, decision-making, and reaction times, making driving while drowsy a dangerous risk on the road. Workers whose job involves long hours of driving, shift work, or a long commute, are at increased risk of driving fatigue. Factors in driving fatigue include: • lack of sleep due to long or irregular shift work hours; • poor sleep quality; • driving during normal sleeping hours (midnight to 6 am); •